Scoliosis is a sideways curvature of the spine, which is often associated with adolescence. However, research has increasingly shown a significant link between scoliosis and menopause, particularly in older women. The hormonal changes that occur during and after menopause can directly influence spinal health. These changes can potentially lead to the development or worsening of a spinal curve.
The Role of Estrogen and Bone Health
Menopause is marked by a significant decline in estrogen levels. While estrogen is a key reproductive hormone, it also plays a crucial role in maintaining bone density. The reduction of estrogen leads to accelerated bone loss, a condition known as osteoporosis.1 This weakening of the bones is the primary reason for the connection between menopause and scoliosis.
The spine’s structural integrity depends on strong, dense bones. When the vertebrae become porous and brittle due to osteoporosis, they are less able to support the body’s weight and resist gravitational forces. 2This can compromise spinal strength and lead to the development of a de novo scoliosis (adult-onset degenerative scoliosis) or cause an existing, previously mild curve to progress.
Research Spotlight: A Deeper Look at the Data
Recent studies have provided compelling evidence for the link between menopause and scoliosis.
- Prevalence: Research indicates that the prevalence of scoliosis significantly increases in postmenopausal women. In fact, the prevalence of clinically significant scoliosis rose from 11.5% in the youngest postmenopausal group to 27.3% among women aged 74–78, and reached 39.4% in those aged 84–88.3
- Hormonal Influence: A key factor in adult-onset scoliosis is low bone mineral density, which often results from the decline in estrogen during and after menopause. 1 As bones weaken, the spine becomes more vulnerable to asymmetric forces, leading to a gradual, progressive curvature. This type of curve most often develops in the lumbar (lower back) region.
- Progression: Women with mild adolescent idiopathic scoliosis may experience rapid bone loss during the postmenopausal years. This can worsen the curve, leading to increased pain and functional limitations.3
These findings underscore the importance of considering spinal health as an integral part of women’s health during and after the menopausal transition.
Clinical Manifestations
Symptoms of adult-onset scoliosis often include:
- Persistent back pain
- Noticeable change in posture
- A sensation of leaning to one side
- In severe cases, nerve compression leading to numbness or weakness in the legs
Management Strategies
Managing scoliosis during and after menopause requires a multidisciplinary approach:
- Bone Health: Prioritize bone density through a nutrient-rich diet (including calcium, vitamin D, and vitamin K2) and, when necessary, medications for osteoporosis.6
- Exercise Therapy: Postural exercises and scoliosis-specific therapeutic exercises with a qualified therapist to strengthen core muscles, improve flexibility, and maintain spinal alignment.
- Naturopathic Care: Approaches that support hormonal balance and overall wellness can complement medical treatment.
- Surgical Intervention: Reserved for severe, progressive cases that significantly impact quality of life and do not respond to conservative treatment.
A Note on Gender Differences
Scoliosis shows a striking difference in prevalence between men and women:
- In adolescence, the female-to-male ratio ranges from 1.5:1 to 3:1 and increases significantly with increasing age.7
- In adulthood, this gap becomes even more pronounced with de novo scoliosis (adult-onset scoliosis). Approximately 34% of women are affected compared to 22% of men. Age also plays a significant role. Scoliosis is observed in approximately 10% of adults under 60. This increases to nearly 29% in those over 60.8
Conclusion
The connection between scoliosis and menopause highlights the importance of recognizing spinal health as a key part of women’s overall well-being during midlife and beyond. As estrogen levels decline and bone health becomes more vulnerable, the risk of developing or worsening scoliosis increases significantly.
By prioritizing bone strength, embracing a multidisciplinary approach to management, and seeking care tailored to hormonal and musculoskeletal changes, women can protect their mobility and quality of life. Recognizing this connection empowers women to embrace healthy lifestyle choices and targeted exercises that strengthen the spine, supporting them to thrive through menopause and beyond.
References:
- Pouresmaeili, F., Kamalidehghan, B., Kamarehei, M., & Goh, Y. M. (2018). A comprehensive overview on osteoporosis and its risk factors. Therapeutics and Clinical Risk Management, 14, 2029–2049. https://doi.org/10.2147/TCRM.S138000 (PMCID: PMC6225907) ↩︎
- Sarioglu O, Gezer S, Sarioglu FC, Koremezli N, Kara T, Akcali O, Ozaksoy D, Balci A. Evaluation of vertebral bone mineral density in scoliosis by using quantitative computed tomography. Pol J Radiol. 2019 Feb 25;84:e131-e135. doi: 10.5114/pjr.2019.84060. PMID: 31019606; PMCID: PMC6479145. ↩︎
- Rubin J, Cleveland RJ, Padovano A, Hu D, Styner M, Sanders J. Lumbar Scoliosis in Postmenopausal Women Increases with Age but is not Associated with Osteoporosis. J Endocr Soc. 2021 Feb 15;5(5):bvab018. doi: 10.1210/jendso/bvab018. PMID: 33855252; PMCID: PMC8023369. ↩︎
- Pouresmaeili, F., Kamalidehghan, B., Kamarehei, M., & Goh, Y. M. (2018). A comprehensive overview on osteoporosis and its risk factors. Therapeutics and Clinical Risk Management, 14, 2029–2049. https://doi.org/10.2147/TCRM.S138000 (PMCID: PMC6225907) ↩︎
- Rubin J, Cleveland RJ, Padovano A, Hu D, Styner M, Sanders J. Lumbar Scoliosis in Postmenopausal Women Increases with Age but is not Associated with Osteoporosis. J Endocr Soc. 2021 Feb 15;5(5):bvab018. doi: 10.1210/jendso/bvab018. PMID: 33855252; PMCID: PMC8023369. ↩︎
- Jiang, M., Li, G., Yang, K., & Tao, L. (2025). Role of vitamins in the development and treatment of osteoporosis (Review). International Journal of Molecular Medicine, 56, 109. https://doi.org/10.3892/ijmm.2025.5550 ↩︎
- Konieczny, M. R., Senyurt, H., & Krauspe, R. (2013). Epidemiology of adolescent idiopathic scoliosis. Journal of Children’s Orthopaedics, 7(1), 3–9. https://doi.org/10.1007/s11832‑012‑0457‑4 (PMCID: PMC3566258)
↩︎ - McAviney, J., Roberts, C., Sullivan, B., et al. (2020). The prevalence of adult de novo scoliosis: A systematic review and meta-analysis. European Spine Journal, 29, 2960–2969. https://doi.org/10.1007/s00586-020-06453-0 ↩︎












